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Natural antisense RNA promotes 3′ end processing and maturation of MALAT1 lncRNA

The RNase P-mediated endonucleolytic cleavage plays a crucial role in the 3′ end processing and cellular accumulation of MALAT1, a nuclear-retained long noncoding RNA that promotes malignancy. The regulation of this cleavage event is largely undetermined. Here we characterize a broadly expressed nat...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zong, Xinying, Nakagawa, Shinichi, Freier, Susan M., Fei, Jingyi, Ha, Taekjip, Prasanth, Supriya G., Prasanth, Kannanganattu V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824109/
https://ncbi.nlm.nih.gov/pubmed/26826711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw047
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