Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB

The long noncoding MALAT1 RNA is upregulated in cancer tissues and its elevated expression is associated with hyper-proliferation, but the underlying mechanism is poorly understood. We demonstrate that MALAT1 levels are regulated during normal cell cycle progression. Genome-wide transcriptome analys...

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Hauptverfasser: Tripathi, Vidisha, Shen, Zhen, Chakraborty, Arindam, Giri, Sumanprava, Freier, Susan M., Wu, Xiaolin, Zhang, Yongqing, Gorospe, Myriam, Prasanth, Supriya G., Lal, Ashish, Prasanth, Kannanganattu V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605280/
https://ncbi.nlm.nih.gov/pubmed/23555285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003368
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