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Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the mono-ace...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158924/ https://ncbi.nlm.nih.gov/pubmed/20709061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.08.013 |
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