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The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

Post-translational histone modifications are crucial for the modulation of chromatin structure and regulation of transcription. Bromodomains present in many chromatin-associated proteins recognize acetylated lysines in the unstructured N-terminal regions of histones. Here, we report that the double...

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Detalhes bibliográficos
Main Authors: LeRoy, Gary, Rickards, Brenden, Flint, S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387119/
https://ncbi.nlm.nih.gov/pubmed/18406326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.018
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