Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails

BACKGROUND: Brd2 is a transcriptional regulator and belongs to BET family, a less characterized novel class of bromodomain-containing proteins. Brd2 contains two tandem bromodomains (BD1 and BD2, 46% sequence identity) in the N-terminus and a conserved motif named ET (extra C-terminal) domain at the...

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Detaylı Bibliyografya
Asıl Yazarlar: Huang, Hongda, Zhang, Jiahai, Shen, Weiqun, Wang, Xingsheng, Wu, Jiawen, Wu, Jihui, Shi, Yunyu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central|1 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065866/
https://ncbi.nlm.nih.gov/pubmed/17848202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-57
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