تحميل...

Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA mutations

Target-matched treatment with PI3K/AKT/mTOR pathway inhibitors in patients with diverse advanced cancers with PIK3CA mutations have shown promise. Tumors from patients with colorectal cancer (CRC) were analyzed for PIK3CA, KRAS and BRAF mutations. PIK3CA mutated tumors were treated, whenever feasibl...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ganesan, Prasanth, Janku, Filip, Naing, Aung, Hong, David S., Tsimberidou, Apostolia M., Falchook, Gerald S., Wheler, Jennifer J., Piha-Paul, Sarina A., Fu, Siqing, Stepanek, Vanda M., Lee, J. Jack, Luthra, Rajyalakshmi, Overman, Michael J., Kopetz, E. Scott, Wolff, Robert A, Kurzrock, Razelle
التنسيق: Artigo
اللغة:Inglês
منشور في: 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158732/
https://ncbi.nlm.nih.gov/pubmed/24092809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0319-T
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