PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers

BACKGROUND: Oncogenic mutations of PIK3CA, RAS (KRAS, NRAS), and BRAF have been identified in various malignancies, and activate the PI3K/AKT/mTOR and RAS/RAF/MEK pathways, respectively. Both pathways are critical drivers of tumorigenesis. METHODS: Tumor tissues from 504 patients with diverse cancer...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Janku, Filip, Lee, J. Jack, Tsimberidou, Apostolia M., Hong, David S., Naing, Aung, Falchook, Gerald S., Fu, Siqing, Luthra, Rajyalakshmi, Garrido-Laguna, Ignacio, Kurzrock, Razelle
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146490/
https://ncbi.nlm.nih.gov/pubmed/21829508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022769
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍