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BRAF Mutations in Advanced Cancers: Clinical Characteristics and Outcomes
BACKGROUND: Oncogenic BRAF mutations have been found in diverse malignancies and activate RAF/MEK/ERK signaling, a critical pathway of tumorigenesis. We examined the clinical characteristics and outcomes of patients with mutant (mut) BRAF advanced cancer referred to phase 1 clinic. METHODS: We revie...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198456/ https://ncbi.nlm.nih.gov/pubmed/22039425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025806 |
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