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Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors
A limited therapeutic arsenal against increasing clinical disease due to Aspergillus spp. necessitates urgent characterisation of new antifungal targets. Here we describe the discovery of novel, low micromolar chemical inhibitors of Aspergillus fumigatus family 18 plant-type chitinase A1 (AfChiA1) b...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158421/ https://ncbi.nlm.nih.gov/pubmed/25063338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.07.015 |
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