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Methods for targeted mutagenesis in zebrafish using TALENs

The transcription activator-like effector (TALE) nucleases, or TALENs, are customizable restriction enzymes that may be used to induce mutations at nearly any investigator-specified DNA sequence in zebrafish. The DNA-binding specificities of TALENs are determined by a protein array comprised of four...

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Main Authors: Hwang, Woong Y., Peterson, Randall T., Yeh, Jing-Ruey Joanna
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157959/
https://ncbi.nlm.nih.gov/pubmed/24747922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.04.009
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