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Degradation of p53, Not Telomerase Activation, by E6 Is Required for Bypass of Crisis and Immortalization by Human Papillomavirus Type 16 E6/E7
Bypass of two arrest points is essential in the process of cellular immortalization, one of the components of the transformation process. Expression of human papillomavirus type 16 E6 and E7 together can escape both senescence and crisis, processes which normally limit the proliferative capacity of...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC415791/ https://ncbi.nlm.nih.gov/pubmed/15140967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5698-5706.2004 |
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