Multiple Functions of Human Papillomavirus Type 16 E6 Contribute to the Immortalization of Mammary Epithelial Cells

The E6 proteins from cervical cancer-associated human papillomavirus (HPV) types such as HPV type 16 (HPV-16) induce proteolysis of the p53 tumor suppressor protein through interaction with E6-AP. We have previously shown that human mammary epithelial cells (MECs) immortalized by HPV-16 E6 display l...

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Detalhes bibliográficos
Main Authors: Liu, Yun, Chen, Jason J., Gao, Qingshen, Dalal, Sorab, Hong, Yihui, Mansur, Claire P., Band, Vimla, Androphy, Elliot J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104255/
https://ncbi.nlm.nih.gov/pubmed/10438818
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