Pattern Recognition Receptor Signaling in Human Dendritic Cells is Enhanced by ICOS Ligand and Modulated by the Crohn’s Disease ICOSLG Risk Allele

Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune homeostasis and cytokine secretion. Multiple loci are associated with IBD, but a functional explanation is missing for most. Here we found that pattern-recognition receptor (PRR)-induced cytokine secretion was dimini...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hedl, Matija, Lahiri, Amit, Ning, Kaida, Cho, Judy H., Abraham, Clara
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157904/
https://ncbi.nlm.nih.gov/pubmed/24837102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.04.011
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares