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Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation

Elongation factor P (EF-P) plays an essential role in the translation of polyproline-containing proteins in bacteria. It becomes functional by the post-translational modification of its highly conserved lysine residue. It is first β-lysylated by PoxA and then hydroxylated by YfcM. In this work, the...

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Hauptverfasser: Kobayashi, Kan, Suzuki, Takehiro, Dohmae, Naoshi, Ishitani, Ryuichiro, Nureki, Osamu
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157426/
https://ncbi.nlm.nih.gov/pubmed/25195899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14015726
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