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The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation

EF-P is a bacterial tRNA-mimic protein, which accelerates the ribosome-catalyzed polymerization of poly-prolines. In Escherichia coli, EF-P is post-translationally modified on a conserved lysine residue. The post-translational modification is performed in a two-step reaction involving the addition o...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Kobayashi, Kan, Katz, Assaf, Rajkovic, Andrei, Ishii, Ryohei, Branson, Owen E., Freitas, Michael A., Ishitani, Ryuichiro, Ibba, Michael, Nureki, Osamu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231759/
https://ncbi.nlm.nih.gov/pubmed/25274739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku898
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