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Recent structural studies on Dom34/aPelota and Hbs1/aEF1α: important factors for solving general problems of ribosomal stall in translation

In the translation process, translating ribosomes usually move on an mRNA until they reach the stop codon. However, when ribosomes translate an aberrant mRNA, they stall. Then, ribosomes are rescued from the aberrant mRNA, and the aberrant mRNA is subsequently degraded. In eukaryotes, Pelota (Dom34...

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Detalhes bibliográficos
Publicado no:Biophysics (Nagoya-shi)
Main Authors: Kobayashi, Kan, Ishitani, Ryuichiro, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society of Japan (BSJ) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629679/
https://ncbi.nlm.nih.gov/pubmed/27493551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.9.131
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