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Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex

No-go decay and nonstop decay are mRNA surveillance pathways that detect translational stalling and degrade the underlying mRNA, allowing the correct translation of the genetic code. In eukaryotes, the protein complex of Pelota (yeast Dom34) and Hbs1 translational GTPase recognizes the stalled ribos...

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Detalhes bibliográficos
Main Authors: Kobayashi, Kan, Kikuno, Izumi, Kuroha, Kazushige, Saito, Kazuki, Ito, Koichi, Ishitani, Ryuichiro, Inada, Toshifumi, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955123/
https://ncbi.nlm.nih.gov/pubmed/20876129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009598107
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