Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations

Translation elongation factor EF1A delivers aminoacyl-tRNA to the ribosome in a GTP-bound form, and is released from the ribosome in a GDP-bound form. This association/dissociation cycle proceeds efficiently via a marked conformational change in EF1A. EF1A function is dependent on the ribosomal “sta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Maruyama, Kei, Imai, Hirotatsu, Kawamura, Momoko, Ishino, Sonoko, Ishino, Yoshizumi, Ito, Kosuke, Uchiumi, Toshio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791870/
https://ncbi.nlm.nih.gov/pubmed/31611569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51266-x
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