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Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding

EngA, a unique GTPase containing a KH-domain preceded by two consecutive G-domains, displays distinct nucleotide binding and hydrolysis activities. So far, Escherichia coli EngA is reported to bind the 50S ribosomal subunit in the guanosine-5′-trihosphate (GTP) bound state. Here, for the first time,...

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Detalhes bibliográficos
Main Authors: Tomar, Sushil Kumar, Dhimole, Neha, Chatterjee, Moon, Prakash, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673443/
https://ncbi.nlm.nih.gov/pubmed/19246542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp107
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