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Omnipotent role of archaeal elongation factor 1 alpha (EF1α) in translational elongation and termination, and quality control of protein synthesis

The molecular mechanisms of translation termination and mRNA surveillance in archaea remain unclear. In eukaryotes, eRF3 and HBS1, which are homologous to the tRNA carrier GTPase EF1α, respectively bind eRF1 and Pelota to decipher stop codons or to facilitate mRNA surveillance. However, genome-wide...

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Autors principals: Saito, Kazuki, Kobayashi, Kan, Wada, Miki, Kikuno, Izumi, Takusagawa, Akira, Mochizuki, Masahiro, Uchiumi, Toshio, Ishitani, Ryuichiro, Nureki, Osamu, Ito, Koichi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984191/
https://ncbi.nlm.nih.gov/pubmed/20974926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009599107
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