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Omnipotent role of archaeal elongation factor 1 alpha (EF1α) in translational elongation and termination, and quality control of protein synthesis

The molecular mechanisms of translation termination and mRNA surveillance in archaea remain unclear. In eukaryotes, eRF3 and HBS1, which are homologous to the tRNA carrier GTPase EF1α, respectively bind eRF1 and Pelota to decipher stop codons or to facilitate mRNA surveillance. However, genome-wide...

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Detalhes bibliográficos
Main Authors: Saito, Kazuki, Kobayashi, Kan, Wada, Miki, Kikuno, Izumi, Takusagawa, Akira, Mochizuki, Masahiro, Uchiumi, Toshio, Ishitani, Ryuichiro, Nureki, Osamu, Ito, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984191/
https://ncbi.nlm.nih.gov/pubmed/20974926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009599107
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