Minor clone provides a reservoir for relapse in multiple myeloma

Recent studies have provided direct evidence for genetic variegation in subclones for various cancer types. However little is known about subclonal evolutionary processes according to treatment and subsequent relapse in multiple myeloma (MM). This issue was addressed in a cohort of 24 MM patients tr...

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Hauptverfasser: Magrangeas, Florence, Avet-Loiseau, Hervé, Gouraud, Wilfried, Lodé, Laurence, Decaux, Olivier, Godmer, Pascal, Garderet, Laurent, Voillat, Laurent, Facon, Thierry, Stoppa, Anne Marie, Marit, Gerald, Hulin, Cyrille, Casassus, Philippe, Tiab, Mourad, Voog, Eric, Randriamalala, Edouard, Anderson, Kenneth C, Moreau, Philippe, Munshi, Nikhil C, Minvielle, Stéphane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157227/
https://ncbi.nlm.nih.gov/pubmed/22874878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.226
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