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Role of additional chromosomal changes in the prognostic value of t(4;14) and del(17p) in multiple myeloma: the IFM experience

In multiple myeloma, cytogenetic changes are important predictors of patient outcome. In this setting, the most important changes are deletion 17p, del(17p), and translocation of chromosomes 4 and 14, t(4;14), conferring a poor outcome. However, a certain degree of heterogeneity is observed in the s...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hebraud, Benjamin, Magrangeas, Florence, Cleynen, Alice, Lauwers-Cances, Valerie, Chretien, Marie-Lorraine, Hulin, Cyrille, Leleu, Xavier, Yon, Edwige, Marit, Gerald, Karlin, Lionel, Roussel, Murielle, Stoppa, Anne-Marie, Belhadj, Karim, Voillat, Laurent, Garderet, Laurent, Macro, Margaret, Caillot, Denis, Mohty, Mohamad, Facon, Thierry, Moreau, Philippe, Attal, Michel, Munshi, Nikhil, Corre, Jill, Minvielle, Stephane, Avet-Loiseau, Herve
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375107/
https://ncbi.nlm.nih.gov/pubmed/25636340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587964
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