The translocation t(4;14) can be present only in minor subclones in multiple myeloma

PURPOSE: Although the translocation t(4;14) is supposed to be a primary event in multiple myeloma, we have been surprised to observe that in large relapse series of patients, the t(4;14) can be observed only in subpopulations of plasma cells, in contrast to what is seen at diagnosis. This observatio...

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Published in:Clin Cancer Res
Main Authors: Hébraud, Benjamin, Caillot, Denis, Corre, Jill, Marit, Gérald, Hulin, Cyrille, Leleu, Xavier, Lodé, Laurence, Wetterwald, Marc, Dib, Mamoun, Rodon, Philippe, Voillat, Laurent, Royer, Bruno, Voog, Eric, Fitoussi, Olivier, Stoppa, Anne-Marie, Garderet, Laurent, Kolb, Brigitte, Maigre, Michel, Boullanger, Nadine, Allangba, Olivier, Karlin, Lionel, Daguindau, Nicolas, Legros, Laurence, Sohn, Claudine, Joubert, Marie-Véronique, Lenain, Pascal, Facon, Thierry, Attal, Michel, Moreau, Philippe, Avet-Loiseau, Hervé
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863228/
https://ncbi.nlm.nih.gov/pubmed/23857603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3866
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