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Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients

Multiple myeloma (MM) develops from a premalignant plasma cell proliferative disorder, and with time can progress to a more aggressive disease in extramedullary locations. The gradually clinical evolution is supported by clonal expansion of cells that acquire genetic lesions over years. This model o...

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Détails bibliographiques
Auteurs principaux: Magrangeas, Florence, Avet-Loiseau, Hervé, Munshi, Nikhil C., Minvielle, Stéphane
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142904/
https://ncbi.nlm.nih.gov/pubmed/21628407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-344069
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