The shaping and functional consequences of the dosage effect landscape in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a malignant proliferation of plasma B cells. Based on recurrent aneuploidy such as copy number alterations (CNAs), myeloma is divided into two subtypes with different CNA patterns and patient survival outcomes. How aneuploidy events arise, and whether they contri...

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Hlavní autoři: Samur, Mehmet K, Shah, Parantu K, Wang, Xujun, Minvielle, Stéphane, Magrangeas, Florence, Avet-Loiseau, Hervé, Munshi, Nikhil C, Li, Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907079/
https://ncbi.nlm.nih.gov/pubmed/24088394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-672
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