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Identification of a Compensatory Mutant (lpg2(−)REV) of Leishmania major Able To Survive as Amastigotes within Macrophages without LPG2-Dependent Glycoconjugates and Its Significance to Virulence and Immunization Strategies

Different Leishmania species rely to different extents on abundant glycoconjugates, such as lipophosphoglycan (LPG) and related molecules, in mammalian infections. Previously, we showed that Leishmania major deletion mutants lacking the Golgi GDP-mannose transporter LPG2, which is required for assem...

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書誌詳細
主要な著者: Späth, Gerald F., Lye, Lon-Fye, Segawa, Hiroaki, Turco, Salvatore J., Beverley, Stephen M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC415719/
https://ncbi.nlm.nih.gov/pubmed/15155672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3622-3627.2004
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