Identification of a Compensatory Mutant (lpg2(−)REV) of Leishmania major Able To Survive as Amastigotes within Macrophages without LPG2-Dependent Glycoconjugates and Its Significance to Virulence and Immunization Strategies

Different Leishmania species rely to different extents on abundant glycoconjugates, such as lipophosphoglycan (LPG) and related molecules, in mammalian infections. Previously, we showed that Leishmania major deletion mutants lacking the Golgi GDP-mannose transporter LPG2, which is required for assem...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Späth, Gerald F., Lye, Lon-Fye, Segawa, Hiroaki, Turco, Salvatore J., Beverley, Stephen M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Fungal and Parasitic Infections
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC415719/
https://ncbi.nlm.nih.gov/pubmed/15155672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3622-3627.2004
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