Clostridium sordellii Lethal Toxin Is Maintained in a Multimeric Protein Complex

Clostridium sordellii lethal toxin (TcsL) is distinct among large clostridial toxins (LCTs), as it is markedly reduced in its rate of intoxication at pH 8.0 yet is cytotoxic at pH 4.0. Results from the present study suggest that TcsL's slow rate of intoxication at pH 8.0 is linked to formation...

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Bibliografiske detaljer
Main Authors: Voth, Daniel E., Qa'Dan, Maen, Hamm, Elaine E., Pelfrey, Joy M., Ballard, Jimmy D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC415707/
https://ncbi.nlm.nih.gov/pubmed/15155642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3366-3372.2004
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