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Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication

Clostridium difficile toxin B (TcdB) has been studied extensively by using cell-free systems and tissue culture, but, like many bacterial toxins, the in vivo targets of TcdB are unknown and have been difficult to elucidate with traditional animal models. In the current study, the transparent Danio r...

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Bibliographic Details
Main Authors: Hamm, Elaine E., Voth, Daniel E., Ballard, Jimmy D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599930/
https://ncbi.nlm.nih.gov/pubmed/16966605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604725103
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