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pH-Enhanced Cytopathic Effects of Clostridium sordellii Lethal Toxin

Clostridium sordellii lethal toxin (TcsL) is a large clostridial toxin (LCT) that glucosylates Ras, Rac, and Ral. TcsL differs from other LCTs because it modifies Ras, which does not cycle from cytosol to membrane. By using a suite of inhibitors, steps in cell entry by TcsL were dissected, and entry...

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Detalhes bibliográficos
Main Authors: Qa'Dan, Maen, Spyres, Lea M., Ballard, Jimmy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98661/
https://ncbi.nlm.nih.gov/pubmed/11500421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5487-5493.2001
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