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New Method To Generate Enzymatically Deficient Clostridium difficile Toxin B as an Antigen for Immunization

The family of the large clostridial cytotoxins, encompassing Clostridium difficile toxins A and B as well as the lethal and hemorrhagic toxins from Clostridium sordellii, monoglucosylate the Rho GTPases by transferring a glucose moiety from the cosubstrate UDP-glucose. Here we present a new detoxifi...

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Hlavní autoři: Genth, Harald, Selzer, Jörg, Busch, Christian, Dumbach, Jürgen, Hofmann, Fred, Aktories, Klaus, Just, Ingo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97253/
https://ncbi.nlm.nih.gov/pubmed/10678912
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