New Method To Generate Enzymatically Deficient Clostridium difficile Toxin B as an Antigen for Immunization

The family of the large clostridial cytotoxins, encompassing Clostridium difficile toxins A and B as well as the lethal and hemorrhagic toxins from Clostridium sordellii, monoglucosylate the Rho GTPases by transferring a glucose moiety from the cosubstrate UDP-glucose. Here we present a new detoxifi...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Genth, Harald, Selzer, Jörg, Busch, Christian, Dumbach, Jürgen, Hofmann, Fred, Aktories, Klaus, Just, Ingo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10678912/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.3.1094-1101.2000
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