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Molecular architecture of mammalian nitric oxide synthases

NOSs are homodimeric multidomain enzymes responsible for producing NO. In mammals, NO acts as an intercellular messenger in a variety of signaling reactions, as well as a cytotoxin in the innate immune response. Mammals possess three NOS isoforms— inducible, endothelial, and neuronal NOS—that are co...

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Bibliografiske detaljer
Main Authors: Campbell, Melody G., Smith, Brian C., Potter, Clinton S., Carragher, Bridget, Marletta, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156747/
https://ncbi.nlm.nih.gov/pubmed/25125509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413763111
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