Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice

Psoriasis (Ps) and psoriasis arthritis (PsA) are poorly understood common diseases, induced by unknown environmental factors, affecting skin and articular joints. A single i.p. exposure to mannan from Saccharomyces cerevisiae induced an acute inflammation in inbred mouse strains resembling human Ps...

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Detalhes bibliográficos
Principais autores: Khmaladze, Ia, Kelkka, Tiina, Guerard, Simon, Wing, Kajsa, Pizzolla, Angela, Saxena, Amit, Lundqvist, Katarina, Holmdahl, Meirav, Nandakumar, Kutty Selva, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156700/
https://ncbi.nlm.nih.gov/pubmed/25136095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405798111
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