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Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
Cytotoxic T lymphocyte antigen-4 (CTLA-4) is essential for immunological (self-) tolerance, but due to the early fatality of CTLA-4 KO mice, its specific function in central and peripheral tolerance and in different systemic diseases remains to be determined. Here, we further examined the role of CT...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855592/ https://ncbi.nlm.nih.gov/pubmed/27071130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603892113 |
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