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Probing α-3(10) Transitions in a Voltage-Sensing S4 Helix

The S4 helix of voltage sensor domains (VSDs) transfers its gating charges across the membrane electrical field in response to changes of the membrane potential. Recent studies suggest that this process may occur via the helical conversion of the entire S4 between α and 3(10) conformations. Here, us...

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Bibliographische Detailangaben
Hauptverfasser: Kubota, Tomoya, Lacroix, Jérôme J., Bezanilla, Francisco, Correa, Ana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156671/
https://ncbi.nlm.nih.gov/pubmed/25185547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.042
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