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Gating Currents from K(v)7 Channels Carrying Neuronal Hyperexcitability Mutations in the Voltage-Sensing Domain

Changes in voltage-dependent gating represent a common pathogenetic mechanism for genetically inherited channelopathies, such as benign familial neonatal seizures or peripheral nerve hyperexcitability caused by mutations in neuronal K(v)7.2 channels. Mutation-induced changes in channel voltage depen...

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Bibliografski detalji
Glavni autori: Miceli, Francesco, Vargas, Ernesto, Bezanilla, Francisco, Taglialatela, Maurizio
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309409/
https://ncbi.nlm.nih.gov/pubmed/22455920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.004
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