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Gating Currents from K(v)7 Channels Carrying Neuronal Hyperexcitability Mutations in the Voltage-Sensing Domain
Changes in voltage-dependent gating represent a common pathogenetic mechanism for genetically inherited channelopathies, such as benign familial neonatal seizures or peripheral nerve hyperexcitability caused by mutations in neuronal K(v)7.2 channels. Mutation-induced changes in channel voltage depen...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309409/ https://ncbi.nlm.nih.gov/pubmed/22455920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.004 |
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