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Mechanisms That Can Promote Peripheral B Cell Lymphoma in ATM-deficient Mice
The Ataxia Telangiectasia-mutated (ATM) kinase senses DNA double-strand breaks (DSBs) and facilitates their repair. In humans, ATM deficiency predisposes to B- and T-cell lymphomas, but in mice leads only to thymic lymphomas. We tested the hypothesis that increased DSB frequency at a cellular oncoge...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156541/ https://ncbi.nlm.nih.gov/pubmed/24913718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0090 |
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