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Structural mapping of divergent regions in the type 1 ryanodine receptor using fluorescence resonance energy transfer

Ryanodine receptors (RyR) release Ca(2+) to initiate striated muscle contraction. Three highly divergent regions in the RyR protein sequence (DR1, DR2, DR3) are proposed to confer isoform-specific functional properties to the RyRs. We used cell-based fluorescence resonance energy transfer (FRET) mea...

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Autors principals: Mahalingam, Mohana, Girgenrath, Tanya, Svensson, Bengt, Thomas, David D., Cornea, Razvan L., Fessenden, James D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156536/
https://ncbi.nlm.nih.gov/pubmed/25132084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.07.003
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