A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose-tissue inflammation in obesity

The c-Jun NH(2)-terminal kinase (JNK) is a critical determinant of obesity-associated inflammation and glucose intolerance. The upstream mechanisms controlling this pathway are still unknown. Here we report that the levels of the PB1 domain-containing adapter NBR1 correlated with the expression of p...

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Detalhes bibliográficos
Main Authors: Hernandez, Eloy D., Lee, Sang Jun, Kim, Ji Young, Duran, Angeles, Linares, Juan F., Yajima, Tomoko, Müller, Timo D., Tschöp, Matthias H., Smith, Steven R., Diaz-Meco, Maria T., Moscat, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156534/
https://ncbi.nlm.nih.gov/pubmed/25043814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.06.008
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