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MEKK1/JNK signaling stabilizes and activates p53

Activation of the tumor suppressor p53 by stress and damage stimuli often correlates with induction of stress kinases, Jun-NH(2) kinase (JNK). As JNK association with p53 plays an important role in p53 stability, in the present study we have elucidated the relationship between the JNK-signaling path...

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Detalhes bibliográficos
Main Authors: Fuchs, Serge Y., Adler, Victor, Pincus, Matthew R., Ronai, Ze’ev
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27930/
https://ncbi.nlm.nih.gov/pubmed/9724739
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