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MEKK1/JNK signaling stabilizes and activates p53

Activation of the tumor suppressor p53 by stress and damage stimuli often correlates with induction of stress kinases, Jun-NH(2) kinase (JNK). As JNK association with p53 plays an important role in p53 stability, in the present study we have elucidated the relationship between the JNK-signaling path...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Fuchs, Serge Y., Adler, Victor, Pincus, Matthew R., Ronai, Ze’ev
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27930/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10541
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