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SAK-HV Decreases the Self-Ubiquitination of MEKK1 to Promote Macrophage Proliferation via MAPK/ERK and JNK Pathways

SAK-HV is an anti-atherosclerosis recombinant fusion protein developed by our lab. Our study determined that SAK-HV promoted macrophage proliferation, of which the mechanism was explored by both RAW264.7 cells and primary macrophages. Mass spectrometric analysis and co-immunoprecipitation were combi...

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Detalhes bibliográficos
Main Authors: Chao Zhang, Yao Chen, Xiangdong Gan, Zhiguang Huang, Minji Zou, Wenliang Fu, Weiwei Xing, Donggang Xu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-04-01
Colecção:International Journal of Molecular Sciences
Assuntos:
ERK
JNK
Acesso em linha:http://www.mdpi.com/1422-0067/18/4/835
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