Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site

Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum. This combination is usually less effective against Plasmodium vivax, probably due to the innate refractoriness of parasites to the sulfadoxine component. To in...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Korsinczky, Michael, Fischer, Katja, Chen, Nanhua, Baker, Joanne, Rieckmann, Karl, Cheng, Qin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2004
Θέματα:
Mechanisms of Resistance
Διαθέσιμο Online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155224/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2214-2222.2004
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