Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site

Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum. This combination is usually less effective against Plasmodium vivax, probably due to the innate refractoriness of parasites to the sulfadoxine component. To in...

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Detalhes bibliográficos
Main Authors: Korsinczky, Michael, Fischer, Katja, Chen, Nanhua, Baker, Joanne, Rieckmann, Karl, Cheng, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415609/
https://ncbi.nlm.nih.gov/pubmed/15155224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2214-2222.2004
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