Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site

Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum. This combination is usually less effective against Plasmodium vivax, probably due to the innate refractoriness of parasites to the sulfadoxine component. To in...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Korsinczky, Michael, Fischer, Katja, Chen, Nanhua, Baker, Joanne, Rieckmann, Karl, Cheng, Qin
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2004
الموضوعات:
Mechanisms of Resistance
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC415609/
https://ncbi.nlm.nih.gov/pubmed/15155224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2214-2222.2004
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