Open Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat Diet

Metabolic diseases result from multiple genetic and environmental factors. We report here that one manner in which environmental factors can contribute to metabolic disease progression is through modification to chromatin. We demonstrate that high fat diet leads to chromatin remodeling in the livers...

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Main Authors: Leung, Amy, Parks, Brian W., Du, Juan, Trac, Candi, Setten, Ryan, Chen, Yin, Brown, Kevin, Lusis, Aldons J., Natarajan, Rama, Schones, Dustin E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156056/
https://ncbi.nlm.nih.gov/pubmed/25006255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581439
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