G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors

BACKGROUND: The formation of chromatin domains is an important step in lineage commitment. In human hematopoietic stem and progenitor cells (HSPCs), G9a/GLP-dependent H3K9me2 chromatin territories form de novo during lineage specification and are nucleated at punctate sites during lineage commitment...

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Autores principales: Schones, Dustin E, Chen, Xiaoji, Trac, Candi, Setten, Ryan, Paddison, Patrick J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166411/
https://ncbi.nlm.nih.gov/pubmed/25237399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-7-23
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