Chromatin variation associated with liver metabolism is mediated by transposable elements

BACKGROUND: Functional regulatory regions in eukaryotic genomes are characterized by the disruption of nucleosomes leading to accessible chromatin. The modulation of chromatin accessibility is one of the key mediators of transcriptional regulation, and variation in chromatin accessibility across ind...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Du, Juan, Leung, Amy, Trac, Candi, Lee, Michael, Parks, Brian W., Lusis, Aldons J., Natarajan, Rama, Schones, Dustin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939004/
https://ncbi.nlm.nih.gov/pubmed/27398095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0078-0
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