Chromatin variation associated with liver metabolism is mediated by transposable elements

BACKGROUND: Functional regulatory regions in eukaryotic genomes are characterized by the disruption of nucleosomes leading to accessible chromatin. The modulation of chromatin accessibility is one of the key mediators of transcriptional regulation, and variation in chromatin accessibility across ind...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Epigenetics Chromatin
Main Authors: Du, Juan, Leung, Amy, Trac, Candi, Lee, Michael, Parks, Brian W., Lusis, Aldons J., Natarajan, Rama, Schones, Dustin E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939004/
https://ncbi.nlm.nih.gov/pubmed/27398095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0078-0
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