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Open Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat Diet

Metabolic diseases result from multiple genetic and environmental factors. We report here that one manner in which environmental factors can contribute to metabolic disease progression is through modification to chromatin. We demonstrate that high fat diet leads to chromatin remodeling in the livers...

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Библиографические подробности
Главные авторы: Leung, Amy, Parks, Brian W., Du, Juan, Trac, Candi, Setten, Ryan, Chen, Yin, Brown, Kevin, Lusis, Aldons J., Natarajan, Rama, Schones, Dustin E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156056/
https://ncbi.nlm.nih.gov/pubmed/25006255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581439
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